Out of nowhere the market for weight loss drugs has become one of the most exciting investment themes in the last two years, rivalling investor enthusiasm for AI.There is good reason for the excitement. Rod Wong, managing partner at RTW Biotech Opportunities (RTW) fund describes the development of obesity drugs as the biggest ever financial opportunity in healthcare.That is because obesity is the

MIGO Opportunities (MIGO) 352pMarket cap: £71.25 millionDiscount to NAV: 4%With many investment trusts trading at deep discounts to NAV (net asset value), a great way to exploit the potential for discounts to narrow is by investing in specialist closed-end fund investor MIGO Opportunities Trust (MIGO).The company has a unique mandate within the sector aimed at exploiting pricing inefficiencies at

Stock prices in London, Paris and Frankfurt were higher at midday Tuesday, with London's FTSE 100 up slightly despite oil major BP losing ground as it eyes lower production figures.Meanwhile in the UK, Chancellor Rachel Reeves will move to reassure turbulent markets amid high government borrowing costs as she faces a grilling from MPs later today.The UK chancellor will answer questions in the Hous

Blue chips in London, Paris and Frankfurt opened lower on Monday as UK Chancellor Rachel Reeves failed to lift the mood in the UK with her China trip, amid a modest investment deal.'Surprise! The US economy added more than [250,000] new nonfarm jobs in December, some [90,000] more than expected, and the unemployment rate fell to 4.1%,' explained Swissquote's Ipek Ozkardeskaya. 'If it's any comfort

Key UK retailers ended Thursday firmly in the red but calmer bond markets and rising commodity prices helped keep blue-chip stocks in the green.The FTSE 100 index ended up 68.66 points, 0.8%, at 8,319.69. The FTSE 250 climbed 52.90 points, 0.3%, at 20,005.14, bouncing from an intra-day low of 19,733.12. The AIM All-Share ended down 0.15 of a point, 0.1%, at 719.96.The Cboe UK 100 closed up 0.8% at

London's blue-chips were higher around midday on Thursday, but fresh falls in the pound and bond market angst kept domestically-focused stocks on the back foot.The FTSE 100 index was up 46.80 points, 0.6%, at 8,297.83. The FTSE 250 was down 95.22 points, 0.5%, at 19,857.02, and the AIM All-Share lost 0.68 of a point, 0.1%, at 719.43.The Cboe UK 100 was up 0.6% at 830.81, the Cboe UK 250 lost 0.5%

Stock prices in London were mixed on Thursday morning, with the FTSE 100 edging higher, despite retailers Tesco and M&S falling after festive trading updates.The FTSE 100 index opened up 11.69 points, 0.1%, at 8,262.72. The FTSE 250 was down 118.85 points, 0.6%, at 19,833.39, and the AIM All-Share lost 0.63 of a point, 0.1%, at 719.48.The Cboe UK 100 was up 0.3% at 827.88, the Cboe UK 250 lost 0.6

The FTSE 100 made a tepid-at-best start to trading on Wednesday, with Shell declining after it forecast a weaker fourth-quarter output performance for its Integrated Gas unit.The FTSE 100 index opened down just 0.69 of a point at 8,244.59. The FTSE 250 was down 24.85 points, 0.1%, at 20,325.52, and the AIM All-Share was up just 0.18 of a point at 725.46.The Cboe UK 100 was down 0.1% at 825.45, the

UK indices closed Monday in the green amid Canadian Prime Minister Justin Trudeau tendering his resignation and reports of a possible watering down of Trump's tariff agenda.The FTSE 100 index ended up 25.68 points, 0.3%, at 8,249.66. The FTSE 250 climbed 21.25 points, 0.1%, at 20,612.65. The AIM All-Share rose 3.55 points, 0.5%, at 728.95.The Cboe UK 100 closed up 0.2% at 826.32, the Cboe UK 250 f

London's blue chip index was slightly in the red on Friday midday, while US markets are expected to open higher after a weak start on Wall Street on Thursday.The FTSE 100 index traded down 4.69 points, 0.1%, at 8,255.40. The FTSE 250 was down 48.37 points, 0.2%, at 20,591.86, and the AIM All-Share was up just 0.19 of a point at 723.54.The Cboe UK 100 was down 0.1% at 827.28, the Cboe UK 250 was 0.

London's blue chip index opened in the red on Friday morning, following a healthy start to the new year, after stocks in New York declined on Thursday.The FTSE 100 index opened down 5.86 points, 0.1%, at 8,254.23. The FTSE 250 was down 51.56 points, 0.3%, at 20,588.67, and the AIM All-Share was down just 0.01 of a point at 723.69.The Cboe UK 100 was flat at 827.68, the Cboe UK 250 was 0.1% lower a

Equities in Europe declined on Monday, in holiday-thinned trade, while declines in New York were more dramatic, with tech stocks bearing the brunt.The FTSE 100 index ended down 28.77 points, 0.4%, at 8,121.01. The FTSE 250 shed 84.10 points, 0.4%, at 20,404.55, and the AIM All-Share lost 0.89 of a point, 0.1%, at 714.23.The Cboe UK 100 ended down 0.2% at 814.55, the Cboe UK 250 fell 0.4% at 17,858

Stocks in London remained in the red at midday on Monday, trimming a year-to-date gain which already fell short of loftier progress in US stocks.The FTSE 100 index traded down 15.85 points, 0.2%, at 8,133.93. The FTSE 250 was down 62.74 points, 0.3%, at 20,425.91, and the AIM All-Share was up just 0.34 of a point at 715.53.The Cboe UK 100 was down 0.1% at 815.90, the Cboe UK 250 down 0.2% at 17,88

UK water firms had their gains pulled back by Friday's close following yesterday's Ofwat induced bump, as Trump threatened the EU with tariff's if it failed to address its trading deficit.The FTSE 100 index closed down 12.67 points, 0.2%, at 8,092.65. The FTSE 250 ended up 31.24 points, 0.2%, at 20,430.62, and the AIM All-Share closed down 0.1, or 0.73 of a point, at 711.05.The Cboe UK 100 ended d

UK stocks were down at midday in London on Friday as concerns about the state of the economy persisted off the back of sluggish retail sales figures.In Europe, pharmaceuticals heavyweight Novo Nordisk plummeted 18% in Copenhagen after disappointing data for its weight loss drug CagriSema.The product is seen as a rival to Eli Lilly's Mounjaro and Zepbound obesity treatments. In premarket trading in

Few doubt that 2025 will be another huge year for AI, but when looking for interesting investment opportunities, investors can sometimes allow details to obscure the bigger picture. In our view, Alphabet (GOOG:NASDAQ) remains an outstanding growth business with strong AI levers to pull, currently trading a large discount to other 'Magnificent Seven' stocks.This valuation gap will, we believe, narr

Stock prices opened in the red in London, Paris and Frankfurt on Tuesday, as investors await eurozone trade balance and US industrial production data.The Office for National Statistics reported that UK unemployment, in the three months to the end of October, remained unchanged at 4.3% compared to the three months to the end of September. Growth in average earnings including bonuses picked up to 5.

Stocks in Europe were mixed on Thursday midday ahead of an interest rate decision by the European Central Bank, while New York's Nasdaq Composite is set to ease after storming above the 20,000 point mark.The FTSE 100 index traded up 12.99 points, 0.2%, at 8,314.61. The FTSE 250 tread water. It was down just 0.53 points at 20,972.92. And the AIM All-Share was up 2.74 points, 0.4%, at 740.28.The Cbo

Stock prices in Europe were in the green on Thursday morning, in anticipation of an interest rate cut by the European Central Bank.Meanwhile, the Swiss National Bank enacted a chunkier than expected rate cut on Thursday.The FTSE 100 index traded up 15.34 points, 0.2%, at 8,316.96. The FTSE 250 was down just 5.35 points at 20,968.10, and the AIM All-Share was up 2.16 points, 0.3%, at 739.70.The Cbo

Predicting what will happen to the global economy and markets over the next 12 months is hard enough at the best of times, but with Trump's election victory on 5 November that job has become even more difficult.As Deutsche Bank's head of global economics and thematics Jim Reid put it, the outlook is no longer 'business as usual' which opens up a much wider range of potential outcomes for the globa