Next-generation drug falls shortOver £70 billion wiped off market valueRace is on for launch of oral drugDanish diabetes and obesity drug specialist Novo Nordisk (NOVO-B:CPH) gave investors a nasty surprise on Friday (20 Dec) after revealing its next generation obesity treatment CagriSema fell short of inducing significantly more weight loss than rival Mounjaro made by Eli Lilly (LLY:NYSE), sendi

Second quarter better than feared Sales down in North America, ChinaTurnaround more marathon than sprintFollowing an initial bounce in after-hours trading on Wall Street stoked by better-than-feared second-quarter results (19 December), Nike's (NKE:NYSE) shares stumbled to trade roughly flat on the realisation the sportswear firm's turnaround will take longer than expected.There was also disappoin

UK equities suffered on US exposure as they closed lower on Thursday amid the Bank of England holding interest rates, but warning of 'heightened uncertainty'.UK Prime Minister Keir Starmer pleaded for patience over his drive to improve living standards, warning it 'will take some time' for people to feel the benefits.Starmer hopes changes to planning rules, reforms to regulations and the use of te

2024 targets confirmedCash-flow forecast raised2025 outlook 'resilient'On an off-day for markets, with the FTSE 100 and the All-Share down 1%, facilities management group Serco (SRP) was a rare bright spot following its year-end trading update.The shares gained 8p or 6% to 147p, erasing much of their losses over the last month and indeed year-to-date. SOLID 2024 PERFORMANCEThe group, which

What a mixed year this has turned out to be for Shares' best ideas for 2024.That our one star turn stock was an annuities and lifetime mortgage specialist, even if it was 'screamingly cheap at its current price', as we originally noted, and the supposedly exciting tech growth picks have been dull-to-dismal, might make you hark back to school days studies of Christopher Hill's The World Turned Upsi

1. Tariffs: President-elect Donald Trump has indicated he will impose new tariffs on three of America's leading trading partners. He plans to sign an executive order placing 25% tariffs on goods imported from Canada and Mexico on day one of his presidency, with an additional 10% on goods from China. This is on top of earlier plans for 60% tariffs on China and 10%-20% on all other imports to the Un

The Nasdaq Composite index closed at a record high in mid-December as tech continued to drive returns ahead of the last Federal Reserve policy meeting of the year.Having recently smashed through the 20,000 mark, the index closed at 20,173.89 on 16 December, boosted by sharp jumps for Tesla (TSLA:NASDAQ) and chipmaker Broadcom (AVGO:NASDAQ).The Nasdaq 100 also closed at an all-time high 22,096.66.B

Let's not beat around the bush, January is an awful month. You've just spent a packet on Christmas, your favourite clothes are inexplicably tight, and your efforts to work off a little holiday weight in the gym are hampered by everyone else trying to do exactly the same thing.It's against this backdrop of seasonal wretchedness that HMRC stations its deadline for filling in a tax return, just in ca

UK takeovers moved up a gear in 2024 as predators targeted bigger companies. The average value of deals was £1.07 billion, nearly three times higher than the £390 million average in 2023. In total, there were £49 billion worth of recommended bids versus £17.2 billion last year.A bounty of unloved or underappreciated companies were swept off their feet, signalling the UK market as being 'on sal

Few doubt that 2025 will be another huge year for AI, but when looking for interesting investment opportunities, investors can sometimes allow details to obscure the bigger picture. In our view, Alphabet (GOOG:NASDAQ) remains an outstanding growth business with strong AI levers to pull, currently trading a large discount to other 'Magnificent Seven' stocks.This valuation gap will, we believe, narr

Ongoing conflicts in Ukraine and the Middle East and calls from incoming US president Donald Trump for NATO members to increase defence spending as a percentage of national income will continue to provide a tailwind for the defence sector.AIM-quoted Cohort (CHRT:AIM) is well positioned to benefit from an increase in defence spending and at the first-half results on 11 December, the group disclosed

Pubs group JD Wetherspoon's (JDW) value credentials continue to shine through. According to fund manager Anna Farmbrough at Ninety One the company has doubled its average price advantage over competitors to 40% since the pandemic.Farmbrough notes that a few years ago there were three pubs in her local area while today there is just a single Wetherspoons, demonstrating its ability to benefit as con

Premium mixer drinks company Fevertree Drinks (FEVR:AIM) has had a torrid time of late with the shares down 38% from the highs in the spring of 2024 and down two-thirds from the all-time high in December 2021.On a longer-term basis, the shares are still up 440% since listing on the AIM market in 2014, equivalent to a compound annual growth rate of 15% a year.Recent poor performance is down to a dr

Strange as it may sound, the pandemic turned out to be a blessing in disguise for the auction industry as it forced firms to join the 21st century and offer an online service.Whereas previously many small auction houses were limited to the number of buyers they could accommodate due to lack of physical space, today they can not only tap into their local market but a whole army of online punters at

Alcoholic drinks outfit Diageo (DGE) has endured a rough period of late, partly thanks to problems of its own making. We think that has put the valuation in a place where, if there are signs the business is getting its act together, the shares can deliver significant upside for investors in 2025.Unless there is evidence of improved performance soon then activist investors could be tempted to join

Move will incur one-off cost of £1.2 millionShares fall 12% year-to-dateFull year trading expected to be in lineShares in Zotefoams (ZTF) fell over 7% to 300p in morning trading as the speciality materials maker said it will be winding down the operations of its MuCell business unit which includes its mono-material barrier packaging company ReZorce.ReZorce uses proprietary microcellular foaming t

Credit/debit card firm has $3.9 billion of previous scheme to investS&P 500 companies on track for record buybacks yearMastercard shares have rallied 26% in 2024The board of Mastercard (MA:NYSE) has approved a new share buyback scheme worth $12 billion of its Class A shares, about 1.3% of its total share capital.Mastercard, one half of the world's debit and credit card duopoly with Visa (V:NYSE),

Saba's investment totals £1.5 billionSix of the seven trusts underperformedCompany proposes sacking directorsThe normally-sleepy world of investment trusts received a wake-up call this morning with the publication of a shareholder letter by activist investor Saba Capital Management calling for change at no fewer than seven well-known funds.The firm, which has a history of successfully instigating

Stocks in London were in the green on Wednesday morning, as investors prepare for eurozone inflation data and the US interest rate decision this afternoon.UK consumer price inflation and producer price inflation data came out before the London open.According to the Office for National Statistics, the consumer prices index rose by 2.6% in the 12 months to November, picking up pace on-month from a 2

European stocks were mixed at midday on Tuesday, as new UK unemployment data was unchanged signalling weak job creation.Investors will be eagerly anticipating the US Federal Reserve and Bank of England rate calls this week. The Fed appears very likely to announce its latest cut, while the BoE is expected to keep rates unchanged.The UK Office for National Statistics reported that unemployment in th