US fast track designation for bone cancer treatmentDesignation based on positive dataNo approved therapies exists for diseaseGSK (GSK) announced that the US FDA (Food and Drug Administration) has granted Breakthrough Designation to its experimental antibody drug conjugate candidate GSK'227 for treating a rare kind of bone cancer.Breakthrough Designation Therapy is aimed at advancing the developmen

Both firms grew their market shareSainsbury's update due on ThursdayTesco update due a day laterIt may not look like it from their share prices today, but if the latest supermarket sales figures are anything to go by both Sainsbury's (SBRY) and Tesco (TSCO) had a bumper Christmas.Sainsbury's, which is due to post a trading statement this Friday (10 January), saw its shares dip 4p or 1.5% to 273p,

London stocks opened in the red on Tuesday morning, but FTSE 100-listed retailer Next achieved a gain as it upped its guidance following a healthy Christmas trading period.The FTSE 100 index opened down 23.47 points, 0.3%, at 8,226.19. The FTSE 250 was down 79.56 points, 0.4%, at 20,533.09, and the AIM All-Share was down 1.37 points, 0.2%, at 727.22.The Cboe UK 100 was down 0.3% at 824.16, the Cbo

US surgeon-general calls for warning labelsCancer link underappreciatedShares in beer, wine and spirit-makers under pressureInvestors in a selection of alcohol stocks are nursing portfolio hangovers following the US surgeon-general's call (3 January) for more prominent warning labels on alcoholic drinks to raise awareness of their link to cancer.Alcohol stocks sank on both sides of the Atlantic on

The FTSE 100 underperformed against its peers in Paris and Frankfurt on Monday morning, just as PMI data from France, Germany and the eurozone are coming in, with UK data set to follow.The FTSE 100 index opened down 17.45 points, 0.2%, at 8,206.53. The FTSE 250 was up 36.75 points, 0.2%, at 20,628.15, and the AIM All-Share was up 1.42 points, 0.2%, at 726.82.The Cboe UK 100 was down 0.3% at 822.51

London's blue chip index opened in the red on Friday morning, following a healthy start to the new year, after stocks in New York declined on Thursday.The FTSE 100 index opened down 5.86 points, 0.1%, at 8,254.23. The FTSE 250 was down 51.56 points, 0.3%, at 20,588.67, and the AIM All-Share was down just 0.01 of a point at 723.69.The Cboe UK 100 was flat at 827.68, the Cboe UK 250 was 0.1% lower a

London's FTSE 100 made a solid start to 2025, shaking off underwhelming trade in Asia.The FTSE 100 index opened up 17.71 points, 0.2%, at 8,190.73. The FTSE 250 was up just 9.30 points, at 20,631.91, and the AIM All-Share was up 2.11 points, 0.3%, at 721.74.The FTSE 100 added 5.7% over the course of last year.The Cboe UK 100 was up 0.3% at 821.34, the Cboe UK 250 was 0.1% higher at 18,078.53, and

London's FTSE 100 closed higher on Tuesday in a shortened trading day, securing the strongest annual gain for the index in three years.Advances in New York this year towered over the UK blue-chip index, however. The FTSE 250 registered an even weaker annual gain and the AIM All-Share shrunk over the course of 2024.The FTSE 100 index ended up 52.01 points, 0.6%, at 8,173.02. It is up 5.7% for the y

The FTSE 100 opened in the red on Tuesday morning, as the shortened final day of trading for the year kicked off with some trepidation.Stocks in New York struggled on Monday, trade in Asian equities was unconvincing, and the nerves fed through to Europe on New Year's Eve.The FTSE 100 index opened down 8.35 points, 0.1%, at 8,112.66. It is up 5.0% for the year.The FTSE 250 was up just 9.64 points a

Equities in Europe declined on Monday, in holiday-thinned trade, while declines in New York were more dramatic, with tech stocks bearing the brunt.The FTSE 100 index ended down 28.77 points, 0.4%, at 8,121.01. The FTSE 250 shed 84.10 points, 0.4%, at 20,404.55, and the AIM All-Share lost 0.89 of a point, 0.1%, at 714.23.The Cboe UK 100 ended down 0.2% at 814.55, the Cboe UK 250 fell 0.4% at 17,858

Apple and AMEX lift BerkshireFisher's tech holdings pay offAs we enter the final trading days of 2024 and tot up how our personal investments have done over the course of the year, analysts at CMC Markets (CMCX) have been looking at how the 'gurus' such as Warren Buffett have fared ahead of the release of their year-end 13-F filings.For the record, every US-domiciled fund with more than $100 milli

Stocks in London were subdued on Monday morning, with only a few of the FTSE 100 opening in the green on the last full day of trading in 2024.The FTSE 100 index opened down 29.94 points, 0.4%, at 8,119.84. The FTSE 250 was down 54.73 points, 0.3%, at 20,433.92, and the AIM All-Share was up 0.90 of a point, 0.1%, at 716.09.The Cboe UK 100 was down 0.3% at 814.35, the Cboe UK 250 down 0.2% at 17,888

Share prices in London started lower on Friday after the two-day Christmas break, as investors dissected initial readings on the strength of holiday sales and the weekly reading on US employment.Out on Boxing Day, US seasonally adjusted initial jobless claims were 219,000 in the week that ended this past Saturday, down 1,000 from the previously week's unrevised total of 220,000, the US Department

Stocks in London opened in the green on Tuesday morning but not everyone is feeling the Christmas spirit, with Vistry issuing a profit warning.The FTSE 100 index opened up 21.00 points, 0.3%, at 8,123.72. The FTSE 250 was up 57.64 points, 0.3%, at 20,476.73, and the AIM All-Share was up 3.11 points, 0.4%, at 715.55.The Cboe UK 100 was up 0.3% at 815.18, the Cboe UK 250 was up 0.3% at 17,932.69, an

Stocks in London opened in the red on Monday amid unwelcome domestic GDP and consumer sentiment releases, and in good news for Direct Line Insurance as Aviva finalises its cash offer.British shoppers expect a 'January spending squeeze' according to the British Retail Consortium.The personal financial situation index remained in negative territory, though steady, at minus 3 points. However, the ind

UK water firms had their gains pulled back by Friday's close following yesterday's Ofwat induced bump, as Trump threatened the EU with tariff's if it failed to address its trading deficit.The FTSE 100 index closed down 12.67 points, 0.2%, at 8,092.65. The FTSE 250 ended up 31.24 points, 0.2%, at 20,430.62, and the AIM All-Share closed down 0.1, or 0.73 of a point, at 711.05.The Cboe UK 100 ended d

Ocado still the number one shortRetailers in general unlovedEnergy services stocks drilledShort-selling, or borrowing shares to sell in the hope of buying them back at a lower price, is not something most retail investors have the nerve or the skill-set to pull off as it requires a certain mindset and a willingness to tolerate heavy losses on occasion until your bets come right.For the pros, howev

Stocks in London opened in the red on Friday morning, ahead of the US personal consumption expenditures release and Frasers founder Mike Ashley making a bid for boohoo leadership.UK retail sales volumes rose by 0.2% month-on-month in November, the Office for National Statistics said, improving from a 0.7% fall in October but falling short of the FXStreet-cited market consensus of 0.5% growth. On a

Stocks in London opened lower on Thursday morning following the US Federal Reserve's rate cut yesterday, as investors prepare for the Bank of England's decision this afternoon.The Fed announced another 25 basis point cut as expected, but hinted that that it will be slowing down next year in contrast with its 'jumbo' 50bp cut in September.'The market reaction was very aggressive, of course,' said S

Anyone who has walked past a building site in the UK recently might well have seen Kier (KIE) branding on it. This infrastructure and construction services outfit is actively at work on more than 400 developments across the UK. Having emerged from a difficult period with much stronger foundations, this improvement is not yet reflected in its current valuation, but we think that will change through