US fast track designation for bone cancer treatmentDesignation based on positive dataNo approved therapies exists for diseaseGSK (GSK) announced that the US FDA (Food and Drug Administration) has granted Breakthrough Designation to its experimental antibody drug conjugate candidate GSK'227 for treating a rare kind of bone cancer.Breakthrough Designation Therapy is aimed at advancing the developmen

Drug gets US regulatory fast-trackSecond-phase trials planned for H2Significant need for new treatmentsGlobal biopharma company GSK (GSK) said it had received US Breakthrough Therapy Designation for its investigational antibody-drug to treat patients with extensive-stage small-cell lung cancer.GSK shares dipped 13p or 0.8% to £15.86 on a weak day for UK stocks generally. WHAT DOES IT MEAN?

Porsche AG (P911:ETR) €69.98Market cap: €31.3 billionAt first glance it may look like an odd time to pitch Porsche AG (P911:ETR) to readers, but we have seen many times that fundamentally good companies can be picked up on the relative cheap during testing times, and that's the scenario we now believe is in front of investors.The shares trade under the name of Dr ING F Porsche AG, which

Stock prices were mixed on Thursday midday in London, while water companies rose after Ofwat decided to raise tap water price caps for customers in England and Wales.The FTSE 100 index was up 20.09 points, 0.3%, at 8,213.60. The FTSE 250 was down 5.06 points at 20,922.70, and the AIM All-Share was up 3.69 points, 0.5%, at 776.54.The Cboe UK 100 was up 0.3% at 818.70, the Cboe UK 250 was flat at 18

Leading global automotive distributor Inchcape's (INCH) resilient business model and growth potential remain underappreciated by investors. Now is a great time to buy the shares, which are cheap relative to history.Through its 'Accelerate' strategy, the FTSE 250 company is helping to consolidate a fragmented global market by leveraging its geographic footprint and relationships with car makers. It

Stocks in London began the week in the red, as uninspiring Chinese growth data failed to allay continued fears about the pace of the nation's recovery following the end of its zero-Covid measures late last year.Despite Cartier-owner Richemont reporting first quarter sales growth, luxury retailers were the worst hit, alongside miners.Meanwhile, Gresham House agreeing to a takeover by Searchlight an

Richemont sales boosted by China reboundBut US sales unexpectedly declineChina GDP data weighs on sentimentLuxury goods stocks were on the slide on Monday following weaker-than-expected gross domestic product figures from China, the world's second biggest economy and a massive market for bling, which came in at 6.3% for the second quarter against the 7.3% called for by consensus.Also weighing on s

As auto enthusiasts everywhere know, a Porsche can turn heads like few other sports cars, a principle that seems to hold true for its shares.The shares trade under the name of Dr ING F Porsche AG (P911:ETR), which is a mouthful, so we'll refer to the company as Porsche AG, but interested readers should take note when it comes to searching for the stock on your chosen investment platform.Porsche AG

Alongside the rally in mega cap tech names since January, one of 2023's big themes is the popularity of global luxury goods stocks, with LVMH (MC:EPA), Richemont (CFR:SWX) and Hermès (RMS:EPA) hitting new share price highs amid an extraordinary boom in sales, supported by a demand rebound from China. LVMH even became the first European company to surpass $500 billion in market value.But som

- Mixers minnow partners with major China distributor- Supercharges focus on premium Chinese drinks market- Margins holding up well despite inflationary pressuresShares in East Imperial (EISB) fizzed 28% higher to 4.1p after the ultra-premium mixers minnow signed a long-term distribution deal with Wen Hua Hang Wine Spirits Company, one of China's biggest distributors.This stirred interest in East

A dispiriting cocktail of military tensions and poor economic readings was dulling stock market activity on Wednesday, as investors found plenty of reasons to stay on the sidelines.An OPEC+ meeting on Wednesday and a Bank of England interest rate decision on Thursday also was dissuading risk-taking.The FTSE 100 was marginally lower, down 2.56 points at 7,406.55, midday Wednesday. The FTSE 250 inde

- China comparable sales slump 35%- EMEIA store sales surge 47%- Company maintains medium-term targetsShares in Burberry (BRBY) were the biggest FTSE 100 fallers on Friday, marked down 6% to £15.50 after the British luxury brand reported subdued first quarter comparable store sales growth of just 1% after its revenue performance was impacted by severe lockdowns in mainland China.The good news is

Rapid recovery growth, a sharp technological edge and decent pricing power, born in Britain technology company Quixant (QXT:AIM) is on the up again after falling from its previous lofty perch.Quixant is a Cambridge-based developer of logic boxes that control pay-to-play digital gaming machines. Think the one arm bandits, quizzes, bingo, casino games and more that you see in pubs and betting shops

Specialty biotech company Shield Therapeutics (STX:AIM) is at an exciting point in its development and is worth buying before the market switches on to its full potential.It is due to launch its proprietary iron deficiency drug Accrufer into the US market at the beginning of June 2021, after raising fresh equity of £29.2 million in March.The product is a novel, low dose oral iron replacement ther

In 2021, as we move into the recovery phase of the coronavirus crisis, emerging markets are rebounding sharply. In this article we explore why you should consider investing in this space and the case for looking at some of the less well-explored options alongside the dominant Chinese market.2020 proved a very up and down year for emerging markets (EM), which plunged to record lows in March amid th

As the share price uptrend shows, investors are regaining an appetite for US-listed Kraft Heinz, the branded food and beverage behemoth where legendary investor Warren Buffett holds considerable sway.Yet the $46.3 billion cap remains modestly valued for a global consumer staples giant due to worries over debt levels and the post-pandemic earnings outlook. Next debt is forecast to be $25.56 billion

Eyewear frames specialist Inspecs (SPEC:AIM) joined the stock market in February after raising £23.5m of new money by issuing stock at 195p. The Bath-based personal goods play got its IPO away before the coronavirus pandemic roiled equity markets and forced governments around the world to shut down their economies.Inspecs has an eye-catching growth story to tell, eventually expects to pay a divid

Shares in Venture Life (VLG:AIM) leapt almost 30% higher to 64.5p on Monday after the consumer self-care company announced its largest-ever contract win with the signing of a new and exclusive agreement with its existing Chinese partner for mouthwash brand Dentyl.Worth a minimum of €168m, the 15-year tie-up with its unnamed Chinese partner covers the distribution of products in Greater China

Shares in aviation services group John Menzies (MNZS) rose 1.2% to 255p despite suspending its dividend, reporting a fall in profit and warning of a 'very disappointing' headwind from the coronavirus.The firm has decided to suspend its dividend as it looks to pay down debt and get its balance sheet back on track, something which hasn't been helped by the virus outbreak.Providing airport services a

A number of global, emerging market and thematic investment trusts put money to work in China, but there are just two dedicated China trusts within the investment companies sector, namely JPMorgan Chinese (JMC) and Fidelity China Special Situations (FCSS). This pair have had a tough time of late.The US/China trade dispute continues to weigh heavily on sentiment, credit growth is slowing and China'