GSK (GSK) announced that the US FDA (Food and Drug Administration) has granted Breakthrough Designation to its experimental antibody drug conjugate candidate GSK'227 for treating a rare kind of bone cancer. Breakthrough Designation Therapy is aimed at advancing the development and review of drugs which have the potential to treat a serious condition and where preliminary evidence suggests a 'su...

It may not look like it from their share prices today, but if the latest supermarket sales figures are anything to go by both Sainsbury's (SBRY) and Tesco (TSCO) had a bumper Christmas. Sainsbury's, which is due to post a trading statement this Friday (10 January), saw its shares dip 4p or 1.5% to 273p, while shares in Tesco, which reports this Thursday, edged 4.7p or 1.3% lower at 368p. LET TH...

London stocks opened in the red on Tuesday morning, but FTSE 100-listed retailer Next achieved a gain as it upped its guidance following a healthy Christmas trading period. The FTSE 100 index opened down 23.47 points, 0.3%, at 8,226.19. The FTSE 250 was down 79.56 points, 0.4%, at 20,533.09, and the AIM All-Share was down 1.37 points, 0.2%, at 727.22. The Cboe UK 100 was down 0.3% at 824.16, th...

UK indices closed Monday in the green amid Canadian Prime Minister Justin Trudeau tendering his resignation and reports of a possible watering down of Trump's tariff agenda. The FTSE 100 index ended up 25.68 points, 0.3%, at 8,249.66. The FTSE 250 climbed 21.25 points, 0.1%, at 20,612.65. The AIM All-Share rose 3.55 points, 0.5%, at 728.95. The Cboe UK 100 closed up 0.2% at 826.32, the Cboe UK...

A PCA (person closely associated) with Shravin Mittal, non-executive director at Airtel Africa (AAF) - a subsidiary of Indian telecoms giant Bharti Airtel - bought 15 million shares in the communications company at 105p for a total value of £15.75 million on 2 January. Airtel is majority-owned by Bharti Airtel, an Indian multinational firm and subsidiary of Bharti Global, the investment arm of...

London's blue chip index was up milder than its peers in Paris and Frankfurt at Monday midday, as UK service sector growth for December was softer than anticipated. As well as Monday's composite and services PMI readings, the first full trading week of 2025 has various jobs data releases from the US culminating in Friday's nonfarm payrolls. More than half of UK companies plan to raise prices by...

Investors in a selection of alcohol stocks are nursing portfolio hangovers following the US surgeon-general's call (3 January) for more prominent warning labels on alcoholic drinks to raise awareness of their link to cancer. Alcohol stocks sank on both sides of the Atlantic on 3 January, among them Jack Daniel's distiller Brown-Forman (BF.B:NYSE), the world's second largest wine and spirits mak...

The FTSE 100 underperformed against its peers in Paris and Frankfurt on Monday morning, just as PMI data from France, Germany and the eurozone are coming in, with UK data set to follow. The FTSE 100 index opened down 17.45 points, 0.2%, at 8,206.53. The FTSE 250 was up 36.75 points, 0.2%, at 20,628.15, and the AIM All-Share was up 1.42 points, 0.2%, at 726.82. The Cboe UK 100 was down 0.3% at 8...

London's FTSE 100 ended lower on Friday, as a sharp sell-off in alcohol makers, spurred by US calls for cancer warning labels on alcoholic beverages, weighed on the index alongside weak housebuilders, despite gains in oil majors Shell and BP and a bright start on Wall Street. The FTSE 100 index ended down 36.11 points, 0.4%, at 8,223.98. The FTSE 250 fell 48.83 points, 0.2%, at 20,591.40. But t...

London's blue chip index was slightly in the red on Friday midday, while US markets are expected to open higher after a weak start on Wall Street on Thursday. The FTSE 100 index traded down 4.69 points, 0.1%, at 8,255.40. The FTSE 250 was down 48.37 points, 0.2%, at 20,591.86, and the AIM All-Share was up just 0.19 of a point at 723.54. The Cboe UK 100 was down 0.1% at 827.28, the Cboe UK 250 w...

Pharmaceutical firm GSK (GSK) said it has received approval from the China Medical Products Administration for Nucula, its monoclonal antibody treatment for adults with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP). It is the third indication to be approved in China for adults with CRSwNP for whom therapy with systematic corticosteroids and or surgery do not provide...

US markets struggled over the festive period, giving up some of their hard-fought gains to end the week between Christmas and the New Year lower. The S&P 500 and the Nasdaq remain slightly above their pre-election levels, but the Dow Industrials and the broad Russell 2000 index are more or less flat on where they were two months ago. Still, that shouldn't detract from the fact the S&P 500 had a...

London's blue chip index opened in the red on Friday morning, following a healthy start to the new year, after stocks in New York declined on Thursday. The FTSE 100 index opened down 5.86 points, 0.1%, at 8,254.23. The FTSE 250 was down 51.56 points, 0.3%, at 20,588.67, and the AIM All-Share was down just 0.01 of a point at 723.69. The Cboe UK 100 was flat at 827.68, the Cboe UK 250 was 0.1% lo...